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This phase, 1/2, which is estimated to begin in December 2025, aims to determine the maximum tolerated dose and safety and tolerability of adding NAC to ovarian cancer patients who are receiving a platinum-based therapy

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These findings point to a predilection for the formation of 2-HB rather than 2-AB due to enhanced lipid oxidation and oxidative stress, which are the results of increased circulating free radicals or a disruption in the antioxidant systems (72, 80)